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Brilliant Blue G receptor br Acknowledgments This research w
2020-03-17
Acknowledgments This research was financially supported by National Natural Science Foundation of China, Nos. 31500926 and 81503282, Natural Science Fund of Guangdong Province, No 2014A030310023, Science and Technology Plan of Guangdong Province, Nos. 2014A020212309, 2013B010404044, 2017A01010501
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br Disclosure statement br Acknowledgements This research wa
2020-03-17
Disclosure statement Acknowledgements This research was supported by grants from the National Institutes of Health, NS046400 and AG022971 (SD), and a fellowship from the Korea Research Foundation, KRF-2007-357-E00016 (YTK). The authors thank Dr. Barbara Crain for assistance with the immunologi
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Recent results from our group found that SPMs not
2020-03-17
Recent results from our group found that SPMs, not only play a part in terminating inflammation, but also have a physiological role in conjunctival goblet 795 mg to maintain ocular surface health in the absence of disease. Amongst the SPMs that are effective in the conjunctiva are resolvin D1 (RvD1
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Based on the above background
2020-03-17
Based on the above background, gliptins may exert natriuretic and diuretic effects as well [[112], [119]]. In accordance with this, Girardi and co-workers have demonstrated a physical interplay between DPP-4 and the NHE3 exchanger in the brush-border epithelium of the proximal renal tubule, suggesti
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Although the implication of DA
2020-03-17
Although the implication of DA and glutamate signaling crosstalk in drug-evoked neuronal adaptations is well acknowledged, targeting the cognate receptors to alleviate symptoms is associated with a loss of efficacy over time and the appearance of severe sides effects, likely due to the involvement o
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In the case of high fidelity
2020-03-17
In the case of high-fidelity polymerases, we propose that water is used to achieve negative selection against nucleotide binding. With specialized DNA polymerases, we propose that nucleobase desolvation plays a different yet important role in allowing these enzymes to replicate damaged DNA. In this
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br Conclusion br Acknowledgments br Introduction Arsenic As
2020-03-17
Conclusion Acknowledgments Introduction Arsenic (As) is one of the most toxic metals derived from the natural environment in soil, air and well water. It has two oxidative states: a trivalent form, arsenite, and a pentavalent form, arsenate. The inorganic As is more toxic than organic As. A
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DNA bound Ku proteins recruit
2020-03-16
DNA-bound Ku proteins recruit DNA-PKcs; and thereby translocate into the duplex by one helical turn, leaving DNA-PKcs near the DNA terminus to assist in tethering the broken ends together [25]. In addition to keeping the DSBs in close proximity, DNA-PKcs may prevent exonucleolytic degradation of the
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Within the availability of large number of
2020-03-16
Within the availability of large number of experimental data, it is easy to develop the relation between the mechanical strength and corrosive resistance of the RHA added cement concrete. The developed correlation is given in the following Eq. (4.8). This equation can be used to predict any of the p
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A prominent example of such enzyme is
2020-03-16
A prominent example of such enzyme is the proteasome, a highly promising target not only in cancer, but also in inflammatory and autoimmune diseases. Circulating proteasomes and respective anti-proteasome autoantibodies were detected in serum samples from patients with autoimmune diseases such as mu
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Converging evidence suggests that reduced glutamate transmis
2020-03-16
Converging evidence suggests that reduced glutamate transmission in the LS is linked to increased anxiety-like behaviors (Radulovic et al., 1999, Henry et al., 2006, Bakshi et al., 2002, Liu et al., 2004). Therefore, attenuated CRF1 receptor-mediated excitatory transmission in the LS following ASV-t
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The assessment process is even more difficult when Commercia
2020-03-16
The assessment process is even more difficult when Commercial-Off-The-Shelf (COTS) components – whose internals are partially or totally unknown – come into play. COTS are being increasingly used by the industry to reduce costs and to shorten development (and possibly deployment) time. However, sin
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In summary synthetic routes with moderate to
2020-03-16
In summary, synthetic routes with moderate to high yields have been developed to produce difluoro-dioxolo-benzoimidazol-benzamides including reference standards and , and -desmethylated precursors and , and carbon-11-labeled difluoro-dioxolo-benzoimidazol-benzamides target tracers [C] and [C]. The
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Ten non FH ADH probands
2020-03-16
Ten non-FH ADH probands fulfilled the diagnostic criteria of hyperabsorbers. Table 2 shows the main lipid characteristics of these subjects and of 10 non-hyperabsorber probands used for comparison. There were differences between groups in body mass index, waist circumference and triglycerides. Other
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In summary we show that PE significantly
2020-03-16
In summary, we show that PE significantly ameliorate HCD-induced atherosclerosis in apoE−/− mice. Dietary fiber may influence the intestinal microbiota and thus the circulating levels of SCFAs. SCFAs, such as butyrate, inhibit cholesterol uptake and promote cholesterol excretion from enterocytes. Ou
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